Clashes erupted between Al-Azhar University pro-ousted president Mohamed Morsi students and police in Cairo's Nasr City on Friday.
Meanwhile, less than 48 hours after Egypt's cabinet declared the Muslim Brotherhood a terrorist group,  supporters of the Muslim Brotherhood clashed with police in several locations across the country following Friday prayers.
Two protesters were killed in clashes between pro-Morsi demonstrators and police in Damietta in the northern Delta and Samalut, in Meniya in Upper Egypt.
The ministry of interior said four soldiers were hurt in fierce clashes with demonstrators in Giza.
The ministry also announced that security forces arrested 148 Pro-Morsi protesters including 25 women nationwide.
Earlier on Friday afternoon, Azhar students hurled rocks at police who were deployed outside their hostel gates to prevent them protesting on the streets outside.
The security forces fired teargas and rubber bullets to disperse the protesters.
The students were protesting outside their hostels in solidarity with their colleague who was killed on Thursday.
Mohamed Abdel-Latif, a first year agriculture student, died in clashes between pro-Morsi Al-Azhar students and local residents in Nasr City.
Abdel-Latif is the second Al-Azhar student to be killed during clashes in the past three months.
Protesters clashed with local residents and police in the port city of Damietta after Friday prayers.
Several organisers of a pro-Morsi protest in Maadi, Cairo were arrested, while at least two pro-Morsi rallies were dispersed by security forces in Nasr City.
In Cairo's Zeitoun, security forces prevented protesters from marching to the Qoba presidential palace.
Protesters blocked a road in Giza's Haram before they were dispersed with teargas.
They also torched two police vehicles after attempting to block the nearby Cairo Ringroad.
Twelve Morsi supporters were arrested in Sohag in Upper Egypt for organising an unauthorised protest.
Several pro-Morsi and pro-Muslim Brotherhood marches took place after Friday prayers in Alexandria, Sohag, Fayoum, Bani Souef, Damietta, Behaira and Port Said in response to calls by the Brotherhood-led National Alliance to Support Legitimacy.
On Thursday, an interior ministry spokesperson announced a five-year penalty for participating in a protest organised by the Islamist group.