At least 17 people were killed and 210 wounded in clashes between opponents of ousted Islamist President Mohamed Morsi and those who support him, state TV quotes the health ministry as saying on Friday.
According to the Freedom and Justice Party -- which is the political arm of the Muslim Brotherhood -- 17 people from the Brotherhood have been killed and hundreds were injured in the clashes.
Clashes raged in Cairo and Egypt’s second largest city, Alexandria, where protesters used stones and Molotov cocktails.
A large group of Islamist crossed a bridge over the Nile River in Cairo, clashing with Morsi opponent near Tahrir square and near the state TV building.
Al Arabiya correspondent reported that fire erupted and gun shots were heard near the 6th October Bridge, which is a major route to Tahrir Square.
The youth movement Tamarod, which spearheaded the protests against the Islamist president, said that four of its supporters were injured in the Abdulmin’im Square in Cairo.
There are at least eight provinces in which the Egyptian army and Morsi supporters have clashed on Friday, according to various reports.
Egypt's interim president, Adly Mansour, issued a curfew in northern Sinai, Al Arabiya's correspondent reported.
By 0810 GMT, the Egyptian army had cleared the area around the state TV, Maspero, and 6th October Bridge from Muslim Brotherhood protesters, Al Arabiya's correspondent reported.