AUBMC Structural Cardiology Team Performs the First Transcaval Percutaneous Aortic Valve Replacement in the Middle East and Asia

Press release
Published September 28th, 2017 - 10:30 GMT
Dr. Fadi Sawaya and Dr. Ziyad Ghazzal
Dr. Fadi Sawaya and Dr. Ziyad Ghazzal

The structural cardiology team at the American University of Beirut Medical Center (AUBMC), Department of Internal Medicine, performed the first transcaval percutaneous aortic valve replacement (TAVI) in the Middle East and Asia, a novel alternative for patients with severe aortic stenosis where TAVI is indicated but cannot be performed with conventional methods.

Developed by researchers at the National Institutes of Health and performed in limited centers in the US and Europe, the percutaneous aortic valve replacement through the transcaval approach is a unique and advanced procedure that offers a new access route option to patients eligible for TAVI but whose conditions are contraindicated for the standard femoral artery access and are unable to tolerate an open heart surgery.

Assistant Professor of Medicine in the Department of Internal Medicine, Division of Cardiology, Dr. Fadi Sawaya assisted by Deputy Executive Vice President for Medical Affairs and Founding Director of the Heart and Vascular Clinical Center of Excellence, Dr. Ziyad Ghazzal, performed the recent advent on an elderly lady with high risk severe aortic stenosis. The patient had no surgical options and was not a candidate for the conventional TAVI method through the leg.

Dr. Fadi Sawaya said, “The transcaval route in percutaneous aortic valve replacement proves a viable alternative access option.” He added, “We continue to strive to bring the latest techniques and cutting edge technologies in cardiovascular care to our patients at AUBMC so that they receive the best and most comprehensive care.”

Dr. Ghazzal said, “This  first-of-its-kind procedure in Lebanon and the region is a great proof that even high risk patients can be treated with the latest advances available, and that we, at AUBMC, have a team of highly trained, qualified, and nationally recognized cardiologists who have established a legacy of excellence in cardiovascular medicine.” 

Until 10 years ago, the only way to replace the aortic valve was with open-heart surgery. Transcatheter Aortic Valve Implantation (TAVI) was developed as a minimally invasive technique. Under sedation, a catheter is inserted into either the chest or the groin area and threaded through an artery to the heart to deliver the replacement valve. The original damaged aortic valve is left in place. Once the new valve is set in position and expanded, it pushes the original valve leaflets out of the way and the tissue in the replacement valve takes over the job of regulating blood.

However, TAVI doesn’t work for everyone. When patients have narrow arteries—often due to peripheral artery disease—it becomes difficult to pass the catheter through the femoral artery. In such cases, an open incision in the chest is created to deliver the valve, which prolongs recovery. With transcaval TAVI, the catheter is inserted through the femoral vein instead of the femoral artery. A communication is then delicately created between the vena cava and the aorta by passing the obstructions in the legs. The TAVI procedure is then completed in the usual fashion. After valve placement, the communication is closed percutaneously with a special closure device.

The operation is another proof of AUBMC being on track of achieving its 2020 Vision, being the leading Medical Center in Lebanon, the Middle East and Asia in using state-of-the- art procedures that help in saving lives.

 

Background Information

American University of Beirut

Founded in 1866, the American University of Beirut is a teaching-centered research university based on the American liberal arts model of higher education. AUB has over 9,000 students and over 1,200 instructional faculty members. The University encourages freedom of thought and expression and seeks to graduate men and women committed to creative and critical thinking, lifelong learning, personal integrity, civic responsibility, and leadership.

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