Momoa will play a man who "vows to bring justice to the people responsible for his wife's death while protecting the only family he has left, his daughter," a press release from the streaming service said.
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The project will mark the feature directorial debut of Brian Andrew Mendoza.
Mendoza previously worked as cinematographer-producer on Braven and as an executive producer on Frontier -- both Netflix shows starring Momoa.
The producing team of Sweet Girl will also include Brad Peyton and Jeff Fierson.
"I'm excited to partner with Netflix once again," Momoa said in a statement. "I'm putting a dream team together from Brad and Jeff to my best friend, Brian, who has been my partner for over 10 years. It's a dream come true to collaborate with him and deliver his vision."
Momoa, who turns 40 on Thursday, is also slated to star in 2022's Aquaman 2, as well as a re-imagining of the sci-fi classic, Dune.