The 65-year-old media personality was asked about the divorce - which neither her daughter, 40, or the rapper, 43, have spoken about publicly - during a chat on Friday's The Kyle and Jackie O Show in Australia.
When asked by host Kyle Sandilands how the two are doing, Kris said: 'Well, I think it's always going to be hard anytime... there's a lot of kids, and Kim and Kanye.
'The good thing about our family is that we are there for each other and supportive, so all I want is for those two kids to be happy.
'That's what you want as a mum.'
While vague on the details, she went on: 'I think we all want that for our families, just to be able to have the love and appreciation of one another, and that everyone's OK.'
When asked by Jackie 'O' Henderson if viewers will see details of the divorce in the final season, she said: 'You might. I don't know what they have decided on in the finale, as we haven't even seen the first show yet.
'I'm sure they're putting some final touches. But I think it's just a private time - Kim wanted to deal with this with her own family in her own time, so when she feels like it I'm sure she'll say what she needs to say.'
Kanye and Kim began dating in 2012 and were engaged in 2013 before marrying in a lavish ceremony in May 2014.
The divorce is the first for Kanye and third for Kim, who was previously married to Damon Thomas from 2000 to 2004 and Kris Humphries from 2011 to 2013.
TMZ reported that Kim officially filed for divorce from Kanye in February. The pair share four children together; North, seven, Chicago, three, Saint, five, and Psalm, one.
In recent months, the children have mostly been seen with Kim in Hidden Hills, California, where the family has a $60 million mansion.
Kim recently sat down with Vogue magazine ahead of the last season of Keeping Up With The Kardashians, where she touched upon a 'challenging year'.
The reality star was asked about life beginning to return to normal post COVID-19 pandemic amid her impending divorce from Kanye after nearly seven years of marriage.
She said during the video interview: 'I think this year has been challenging for so many people but I also think that this year was a huge cleanse and just a huge opportunity for people to really be grateful for the simple things and and that is a huge -- I think awakening that some people had,' per Vogue via Page Six.
The mother of four added: 'I always try to look at things in a positive way.'
She continued: 'Even though it has been such a challenging year, it's a time to regenerate, get creative, spend so much time with family and just this time I've been able to spend with my children has been priceless. That part has been so beautiful.'
The beauty was not asked directly about her divorce nor did she speak on it.
The new season of Keeping Up With The Kardashians is available on hayu & E! from Friday.
© Associated Newspapers Ltd.