At least 65 people were killed and 325 injured Wednesday when a car bomb exploded during morning rush hour in Kabul's diplomatic district, the Afghanistan health ministry said.
Police said the blast, described as "one of the biggest" to hit Afghanistan's capital, occurred in Zanbaq Square, close to many government offices and foreign embassies.
"The explosion was so loud that it shattered all my windows," Kabul resident Fatima Faizi told Al Jazeera. "Did not hear something this big before."
The blast was caused by a suicide attack near the German embassy, according to Najib Danish, an Interior Ministry.
"It was a car bomb near the German embassy, but there are several other important compounds and offices near there too," said Kabul police spokesman Basir Mujahid. "It is hard to say what the exact target is."
No group has claimed responsibility for the attack, which police said came from a water tanker truck packed with explosives.
But last month the Taliban announced a "spring offensive" targeting foreign troops.
In April, a Taliban attack on an Afghan army base killed at least 140 soldiers.
Earlier this month, eight people were killed in a suicide bomb attack on a NATO convoy.
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