Israeli forces shot and injured six Palestinians with live rounds and rubber-coated steel bullets during clashes in Bireh north of Ramallah overnight Monday, medics said.
The clashes, which lasted up to 12 hours, also saw dozens of Palestinians suffer excessive tear gas inhalation.
Palestinian protesters threw stones at Israeli forces in the illegal Israeli settlement of Beit El, and the army fired live rounds, rubber-coated steel bullets and tear gas canisters at protesters.
The army later raided parts of al-Bireh, where it was reported that Palestinian gunmen opened fire on them, forcing them out of the northern Ramallah neighborhood.
On Monday evening, a Red Crescent spokeswoman told Ma'an that at least 500 Palestinians had so far been injured in fierce clashes that have swept across the occupied West Bank and East Jerusalem.
At least 41 Palestinians have been shot with live rounds, while 143 have been injured by rubber-coated steel bullets.
Israeli forces have also killed two Palestinians in the same time frame, including a 13-year-old boy in Aida refugee camp on Monday.
The Palestinian Red Cross on Sunday declared a state of emergency across the occupied Palestinian territory, and said it was putting all its staff, teams and volunteers on standby.
The PLO has also warned that attacks by both Israeli soldiers and settlers indicated "the Israeli government is deliberately creating a situation of violence and instability that threatens to spiral out of control."
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