Everton play host to Arsenal at Goodison Park and hope that the friendly Toffee confines are the difference maker again after last season's strong 3-0 victory over Arsene Wenger's side in April.
Manager Roberto Martinez will be without Ross Barkley for the foreseeable future as the young rising star has been sidelined through injury while also Bryan Oviedo and Arouna Kone are ruled out.
Seamus Coleman should be on the pitch from the opening whistle but strong showings from Steven Naismith and Aiden McGeady are likely to see Kevin Mirallas remain on the bench.
However, Arsenal will be out for revenge this go around at Goodison and despite the laundry list of injury for Arsene Wenger that includes; Serge Gnabry, Ryo Miyaichi, Theo Walcott, David Ospina, Kieran Gibbs, and doubtful MIkel Arteta and Yaya Sanogo, it will be a strong Arsenal side.
Per Mertesacker could make his regular season debut on his return from international break while Mathieu Flamini could feature in place of Arteta and Olivier Giroud is expected to be in the first team from the get go.
The returns of also Lukas Podolski and Mesut Ozil to at least the bench will be important as the Gunner's mid-week match in Turkey appeared to take much energy out of the side and Everton will hope to take advantage.
Everton XI: Howard: Coleman, Jagielka, Distin, Baines; McCarthy, Barry; McGeady, Naismith, Pienaar; Lukaku.
Arsenal XI: Szczesny: Debuchy, Chambers, Mertesacker, Monreal; Flamini; Sanchez, Wilshere, Ramsey, Cazorla; Giroud.
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